‘Weaponised’ CAR T-cell therapy shows promise against solid tumours

An illustration of CAR T-cell therapy treating tumour cells Brain light/Alamy Immune cells that have been genetically engineered to kill cancerous cells, known as CAR T-cells, have transformed the treatment of blood cancers such as leukaemia, but have proved largely ineffective against solid tumours. But now, “weaponised” CAR T-cells have eradicated large solid prostate tumours…

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How the CIA’s Kryptos Sculpture Gave Up Its Final Secret

The 35-year-old saga of Kryptos, an enigmatic sculpture containing four encrypted messages outside the CIA headquarters, just took a bizarre twist. Though cryptographers broke the first three passages in the 1990s, just a few years after artist Jim Sanborn erected the copper monolith, the fourth, known as K4, remained a 97-character fortress—that is, until September…

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How to nurture infant microbiomes for a lifetime of good mental health

Families who garden together have more diverse microbiomes Halfpoint Images/Getty Images New parents have plenty to fret about – sleeping, feeding, the colour of their newborn’s poo – but their baby’s microbiome probably isn’t high on the list. According to experts, it should be. “The first 1000 days of life are incredibly important for seeding…

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